Viral infection intervention:
A formula of 6 herbs that have proven capacity for resolving respiratory infections of various kinds and/or they display antiviral, immunomodulating actions*.
Designed to be taken at the onset of and during a viral infection - with a maximum consumption timespan of 14 days (certain herbs begin to lose effectiveness after this time period. This is different to shelf-life, which, at room temperature and out of light is indefinite/very lengthy).
Liquorice (cooling, moistening), angelica (strongly warming, moistening and drying potentials), clematis (strongly warming in chest region), echinacea (cooling, drying), elderberry (cooling, drying – but relieves circulation stagnation which allows moistening, warming properties of herbs to travel upwards), bidens pilosa (neutral).
Recommended dose: 15 drops 3-5 times a day at suspected onset and during a viral infection.
Licorice:
Coronaviruses prefer dry, cool environments to exist and proliferate in, licorice is moistening and will also help to harmonise the rest of the formula.
Broadspectrum antiviral properties. Triterpenoids such as glycyrrhizin from the licorice plant, Glycyrrhiza glabra L., have been reported to have in vitro anti-SARS effects. These natural compounds interfere with virus–host fusion. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271932/
Contains glycyrrhizin which shows a strong anti-SARS-CoV activity (Li et al., 2005a,b).
Glycyrrhizin lowers the ability of SARS-Cov agents to attach to the cell particularly in the early stages of viral infestation.Furthermore, along with Glycyrrhizin it contains flavonoids, β-sitosterol, hydroxyl coumarins and glycyrrhetinic acid, which have been affirmed to have anti-inflammatory and antioxidant potential that induce the formation of interferons in human body. Has been shown to inihibit viral replication or SARS-Cov-2
https://www.sciencedirect.com/science/article/pii/S0944711320301926#bib0228
Angelica Archangelica:
Has been used to treat a variety of upper respiratory illnesses from colds, to flus and pneumonia. It’s essential oils have been scientifically proven to exhibit strong antibacterial, antimicrobial effects (https://www.researchgate.net/profile/Vineet-Maurya-2/publication/352374491_Methanolic_Extract_of_Angelica_glauca_Edgew_Root_and_Stem_A_Possible_Component_of_Herbal_Medicines_against_Respiratory_Infections/links/60c81939299bf108abd963da/Methanolic-Extract-of-Angelica-glauca-Edgew-Root-and-Stem-A-Possible-Component-of-Herbal-Medicines-against-Respiratory-Infections.pdf)Angelica’s roots and seeds contain the constituent ICEP4 which presented significant in vitro cytoprotective effect in highly virulent-SARS-CoV-2 challenged Vero E6 cellular cultures using 34.5 and 69 µM concentration. Prevented viral replication at the targeted epithelium. doses. (https://www.biorxiv.org/content/10.1101/2020.12.04.410340v1.abstract)
Contains Psoralens which are antiviral.
Clematis:
Many members of the family have been shown to have antiviral, antifungal, antibacterial properties with an affinity for infections in the respiratory system.
https://www.sciencedirect.com/science/article/abs/pii/S0378874101003622
https://www.sciencedirect.com/science/article/pii/S2210909914001635http://ischolar.info/index.php/CiiTBB/article/view/106534
Has been shown to be effective against various strains of influenza:
https://www.sciencedirect.com/science/article/pii/S019697810900268X
Echinacea:
Potent lymphatic and immune modulator best used at the onset of acute infections. A timetested anti-viral agent that has recently been shown to exhibit antiviral effect against Sars-Cov-2. https://www.biorxiv.org/content/10.1101/2021.01.11.426295v1.abstract
Also shows specific immunosuppressant activity that suppresses dangerous cytokine cascades that can be caused by covid-19. https://www.sciencedirect.com/science/article/pii/S2405844021000955
*Before purchase please see full disclaimer at bottom of page - statements and products not approved by TGA.
Viral Infection Intervention
Elderberry:
In herbal formulations, both the rose and fruit of mature trees have traditionally been used to treat influenza.
The primary polyphenols in elderberry fruit are chlorogenic acid, neochlorogenic acid, cryptochlorogenic acid, quercetin, quercetin-3-rutinoside (rutin), quercetin-3-glucoside (isoquercitrin), kaempferol-3-rutinoside, kaempferol-3-glucoside (astragalin), isorhamnetin-3-rutinoside and isorhamnetin-3-glucoside. The primary flavanol in this plant is rutin, while the other flavanols, like iso-quercitrin and astragalin, occur in elderberries in smaller amounts [115,116]. Its extracts were used in the early stages of the epidemic, although its supplements have not been tested for coronavirus treatment, randomized, double-blind, placebo-controlled trials and meta-analyses have shown that they effectively treat colds and influenza [117]. There have been extensive reports on the beneficial effects of elderberry products on various viral infections. Few theories have been established on the potential immunological mechanisms for elderberry supplements beneficial effects as they may help reduce upper respiratory symptoms caused by viral infections and help alleviate flu symptoms [118].
https://www.mdpi.com/2227-9059/9/9/1266/htm
Bidens Pilosa/Spanish Needles:
Has shown strong antibacterial activity towards other upper respiratory infections such as tuberculosis, and pneumonia. Also has immunomodulating properties, and the ability to act as a immune trophorestorative.
https://academicjournals.org/journal/JMPR/article-abstract/53B867414735
https://www.researchgate.net/profile/Rajeev-Kumar-142/publication/268367156_An_updated_review_on_Bidens_Pilosa_L/links/54bc905d0cf29e0cb04c0a18/An-updated-review-on-Bidens-Pilosa-L.pdf
Contains Luteolin, and Leutosides which have been shown to inhibit coronavirus entry and fusion with various receptor sites in the body.
https://assets.researchsquare.com/files/rs-35368/v1/4ea5888d-3164-4151-82d8-c396dd80d017.pdf?c=1631843746
Luteolin inhibits serine proteases including the SARS‐CoV 3CL protease required for viral infectivity.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267424/
Luteolin also inhibits mast cell degranulations.
Spanish Needles also contain 10 different forms of Quercetin which have been shown to exhibit significant antiviral effect against covid 19:
https://journals.sagepub.com/doi/full/10.1177/1934578X20976293
Contains Centaurein which has been shown to be safe, with a high binding affinity with studied SARS-CoV-2 target proteins.
https://biointerfaceresearch.com/wp-content/uploads/2021/01/20695837114.1212012148.pdf
